sglt2 inhibitors Search Results


sglt2-inhibitor  (AstraZeneca ltd)
90
AstraZeneca ltd sglt2-inhibitor
Sglt2 Inhibitor, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc11068935-8-48-34?v=AstraZeneca+ltd
Average 90 stars, based on 1 article reviews
sglt2-inhibitor - by Bioz Stars, 2026-07
90/100 stars
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sglt-2 inhibitor empa  (Cayman Chemical)
90
Cayman Chemical sglt-2 inhibitor empa
A <t>ANG-induced</t> <t>SGLT-1</t> protein expression was reduced in the presence of <t>EMPA</t> in H9c2 cardiomyoblasts. Upper : Representative Western Blot of H9c2 cardiomyoblasts cell lysate probed with anti-SGLT-1. Tubulin was used as loading control. Lower : Quantification of SGLT-1 band normalized to tubulin. The bar graph represents the mean value ± SEM of n = 5 independent experiments ( n = 3 for EMPA, and ANG + EMPA).* indicates P < 0.05 vs CTRL. # indicates P < 0.01 vs CTRL. α indicates P < 0.05 vs ANG. B SGLT-2 protein expression of H9c2 cardiomyoblasts with ANG ± EMPA treatment. Representative Western blot of H9c2 cardiomyoblasts cell lysate probed with anti-SGLT-2. Tubulin was used as loading control
Sglt 2 Inhibitor Empa, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc09068664-39-2-6?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
sglt-2 inhibitor empa - by Bioz Stars, 2026-07
90/100 stars
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sglt2 inhibitor empa  (Ark Pharm Inc)
90
Ark Pharm Inc sglt2 inhibitor empa
( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated <t>SGLT2</t> mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.
Sglt2 Inhibitor Empa, supplied by Ark Pharm Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc08891593-51-6-9?v=Ark+Pharm+Inc
Average 90 stars, based on 1 article reviews
sglt2 inhibitor empa - by Bioz Stars, 2026-07
90/100 stars
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sglt2 inhibitors  (Millar Inc)
90
Millar Inc sglt2 inhibitors
( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated <t>SGLT2</t> mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.
Sglt2 Inhibitors, supplied by Millar Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pm40245989-93-1-22?v=Millar+Inc
Average 90 stars, based on 1 article reviews
sglt2 inhibitors - by Bioz Stars, 2026-07
90/100 stars
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encapsulating sglt-2 inhibitor dapagliflozin (dapa)  (NanoCarrier Co)
90
NanoCarrier Co encapsulating sglt-2 inhibitor dapagliflozin (dapa)
( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated <t>SGLT2</t> mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.
Encapsulating Sglt 2 Inhibitor Dapagliflozin (Dapa), supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/10__22203_slash_ecm__v050a02-35-12-11?v=NanoCarrier+Co
Average 90 stars, based on 1 article reviews
encapsulating sglt-2 inhibitor dapagliflozin (dapa) - by Bioz Stars, 2026-07
90/100 stars
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sglt-2 inhibitors  (Verum Diagnostica GmbH)
90
Verum Diagnostica GmbH sglt-2 inhibitors
( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated <t>SGLT2</t> mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.
Sglt 2 Inhibitors, supplied by Verum Diagnostica GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pm37338539-76-17-10?v=Verum+Diagnostica+GmbH
Average 90 stars, based on 1 article reviews
sglt-2 inhibitors - by Bioz Stars, 2026-07
90/100 stars
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lx4211 (sotagliflozin; dual sglt1/ sglt2 inhibitor)  (Advanced ChemBlocks Inc)
90
Advanced ChemBlocks Inc lx4211 (sotagliflozin; dual sglt1/ sglt2 inhibitor)
( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated <t>SGLT2</t> mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.
Lx4211 (Sotagliflozin; Dual Sglt1/ Sglt2 Inhibitor), supplied by Advanced ChemBlocks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pm32130907-304-0-9?v=Advanced+ChemBlocks+Inc
Average 90 stars, based on 1 article reviews
lx4211 (sotagliflozin; dual sglt1/ sglt2 inhibitor) - by Bioz Stars, 2026-07
90/100 stars
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sodium-glucose transport protein 2 inhibitor  (Petra Pharma)
90
Petra Pharma sodium-glucose transport protein 2 inhibitor
( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated <t>SGLT2</t> mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.
Sodium Glucose Transport Protein 2 Inhibitor, supplied by Petra Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc09297732-374-28-9?v=Petra+Pharma
Average 90 stars, based on 1 article reviews
sodium-glucose transport protein 2 inhibitor - by Bioz Stars, 2026-07
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methods for preparing sglt2 inhibitors  (MSD International GmbH)
90
MSD International GmbH methods for preparing sglt2 inhibitors
Genes, substrates and tissue distribution of SGLT proteins <xref ref-type= 42 " width="250" height="auto" />
Methods For Preparing Sglt2 Inhibitors, supplied by MSD International GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc09048284-13-17-8?v=MSD+International+GmbH
Average 90 stars, based on 1 article reviews
methods for preparing sglt2 inhibitors - by Bioz Stars, 2026-07
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ethoxyphenylmethyl inhibitors of sglt2  (Auspex Pharma)
90
Auspex Pharma ethoxyphenylmethyl inhibitors of sglt2
Genes, substrates and tissue distribution of SGLT proteins <xref ref-type= 42 " width="250" height="auto" />
Ethoxyphenylmethyl Inhibitors Of Sglt2, supplied by Auspex Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc09048284-15-15-6?v=Auspex+Pharma
Average 90 stars, based on 1 article reviews
ethoxyphenylmethyl inhibitors of sglt2 - by Bioz Stars, 2026-07
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sglt2 inhibitor remogliflozin etabonate  (Islet Sciences)
90
Islet Sciences sglt2 inhibitor remogliflozin etabonate
Genes, substrates and tissue distribution of SGLT proteins <xref ref-type= 42 " width="250" height="auto" />
Sglt2 Inhibitor Remogliflozin Etabonate, supplied by Islet Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pmc05298360-651-17-10?v=Islet+Sciences
Average 90 stars, based on 1 article reviews
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sglt2 inhibition  (Balzer GmbH)
90
Balzer GmbH sglt2 inhibition
Genes, substrates and tissue distribution of SGLT proteins <xref ref-type= 42 " width="250" height="auto" />
Sglt2 Inhibition, supplied by Balzer GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sglt2+inhibitors/pm35188009-84-13-6?v=Balzer+GmbH
Average 90 stars, based on 1 article reviews
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Image Search Results


A ANG-induced SGLT-1 protein expression was reduced in the presence of EMPA in H9c2 cardiomyoblasts. Upper : Representative Western Blot of H9c2 cardiomyoblasts cell lysate probed with anti-SGLT-1. Tubulin was used as loading control. Lower : Quantification of SGLT-1 band normalized to tubulin. The bar graph represents the mean value ± SEM of n = 5 independent experiments ( n = 3 for EMPA, and ANG + EMPA).* indicates P < 0.05 vs CTRL. # indicates P < 0.01 vs CTRL. α indicates P < 0.05 vs ANG. B SGLT-2 protein expression of H9c2 cardiomyoblasts with ANG ± EMPA treatment. Representative Western blot of H9c2 cardiomyoblasts cell lysate probed with anti-SGLT-2. Tubulin was used as loading control

Journal: Molecular and Cellular Biochemistry

Article Title: Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression

doi: 10.1007/s11010-022-04411-6

Figure Lengend Snippet: A ANG-induced SGLT-1 protein expression was reduced in the presence of EMPA in H9c2 cardiomyoblasts. Upper : Representative Western Blot of H9c2 cardiomyoblasts cell lysate probed with anti-SGLT-1. Tubulin was used as loading control. Lower : Quantification of SGLT-1 band normalized to tubulin. The bar graph represents the mean value ± SEM of n = 5 independent experiments ( n = 3 for EMPA, and ANG + EMPA).* indicates P < 0.05 vs CTRL. # indicates P < 0.01 vs CTRL. α indicates P < 0.05 vs ANG. B SGLT-2 protein expression of H9c2 cardiomyoblasts with ANG ± EMPA treatment. Representative Western blot of H9c2 cardiomyoblasts cell lysate probed with anti-SGLT-2. Tubulin was used as loading control

Article Snippet: SGLT-2 inhibitor, EMPA, was obtained from Cayman Chemical, Michigan, USA.

Techniques: Expressing, Western Blot, Control

( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated SGLT2 mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.

Journal: Bioscience Reports

Article Title: Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy

doi: 10.1042/BSR20212209

Figure Lengend Snippet: ( A ) Blood glucose levels in mice displaying DR. ( B ) Identification of elevated SGLT2 mRNA expression in the whole eyes of mice displaying DR. ( C ) Increased SGLT2 mRNA expression in the kidney medulla of Akimba mice; * P =0.08 compared with WT. ( D ) Raised SGLT2 mRNA expression in the kidney cortex of Akimba mice; ** P =0.048 compared with WT. All data are expressed as mean + SEM; n =1–7 mice/group.

Article Snippet: Following a 7-day acclimatization period, the SGLT2 inhibitor EMPA (Ark Pharma Scientific Limited, China; 25 mg/kg/day) or vehicle (dimethylsulfoxide) was administered to the mice weekly via their drinking water for 8 weeks.

Techniques: Expressing

Positive SGLT2 staining (red arrows) in the retinal ganglion cell layer. Magnification 400×.

Journal: Bioscience Reports

Article Title: Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy

doi: 10.1042/BSR20212209

Figure Lengend Snippet: Positive SGLT2 staining (red arrows) in the retinal ganglion cell layer. Magnification 400×.

Article Snippet: Following a 7-day acclimatization period, the SGLT2 inhibitor EMPA (Ark Pharma Scientific Limited, China; 25 mg/kg/day) or vehicle (dimethylsulfoxide) was administered to the mice weekly via their drinking water for 8 weeks.

Techniques: Staining

Genes, substrates and tissue distribution of SGLT proteins <xref ref-type= 42 " width="100%" height="100%">

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: Genes, substrates and tissue distribution of SGLT proteins 42

Article Snippet: 3 , WO2014159151A1 (US9573959B2, EP3466431A1 , EP2968375B1) , MSD International GmbH , 2014 , Methods for preparing SGLT2 inhibitors , United States, Europe.

Techniques:

Chemical classification of SGLT1/SGLT2 inhibitors.

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: Chemical classification of SGLT1/SGLT2 inhibitors.

Article Snippet: 3 , WO2014159151A1 (US9573959B2, EP3466431A1 , EP2968375B1) , MSD International GmbH , 2014 , Methods for preparing SGLT2 inhibitors , United States, Europe.

Techniques:

In vitro evaluation results of compounds 33–37 against SGLT2 ( <xref ref-type= ref. 99 )" width="100%" height="100%">

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: In vitro evaluation results of compounds 33–37 against SGLT2 ( ref. 99 )

Article Snippet: 3 , WO2014159151A1 (US9573959B2, EP3466431A1 , EP2968375B1) , MSD International GmbH , 2014 , Methods for preparing SGLT2 inhibitors , United States, Europe.

Techniques: In Vitro

Patents on SGLT inhibitors

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: Patents on SGLT inhibitors

Article Snippet: 3 , WO2014159151A1 (US9573959B2, EP3466431A1 , EP2968375B1) , MSD International GmbH , 2014 , Methods for preparing SGLT2 inhibitors , United States, Europe.

Techniques: Activity Assay

Genes, substrates and tissue distribution of SGLT proteins <xref ref-type= 42 " width="100%" height="100%">

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: Genes, substrates and tissue distribution of SGLT proteins 42

Article Snippet: 5 , WO2010048358A2 (US20100167988A1 ) , Auspex Pharmaceutical, Inc. , 2010 , Ethoxyphenylmethyl inhibitors of SGLT2 ( ) , United States.

Techniques:

Chemical classification of SGLT1/SGLT2 inhibitors.

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: Chemical classification of SGLT1/SGLT2 inhibitors.

Article Snippet: 5 , WO2010048358A2 (US20100167988A1 ) , Auspex Pharmaceutical, Inc. , 2010 , Ethoxyphenylmethyl inhibitors of SGLT2 ( ) , United States.

Techniques:

In vitro evaluation results of compounds 33–37 against SGLT2 ( <xref ref-type= ref. 99 )" width="100%" height="100%">

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: In vitro evaluation results of compounds 33–37 against SGLT2 ( ref. 99 )

Article Snippet: 5 , WO2010048358A2 (US20100167988A1 ) , Auspex Pharmaceutical, Inc. , 2010 , Ethoxyphenylmethyl inhibitors of SGLT2 ( ) , United States.

Techniques: In Vitro

Patents on SGLT inhibitors

Journal: RSC Advances

Article Title: SGLT inhibitors as antidiabetic agents: a comprehensive review

doi: 10.1039/c9ra08706k

Figure Lengend Snippet: Patents on SGLT inhibitors

Article Snippet: 5 , WO2010048358A2 (US20100167988A1 ) , Auspex Pharmaceutical, Inc. , 2010 , Ethoxyphenylmethyl inhibitors of SGLT2 ( ) , United States.

Techniques: Activity Assay